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The Food and Drug Administration, FDA, has approved the drug Vivitrol for your treatment of opioid dependence based on a news release by them on 10-12-2010. Using two separate drugs to lose weight naturally can be very effective you can find combinations while watching FDA now awaiting approval. When dealing with fat loss and the those who go through it you need to err along the side of caution and allow the FDA do its job and demand some investigation be done so the public understands the side effects and perils associated with the medications before we take them. Keep in mind that drug companies have been in business to generate money and that they would say anything to keep people on their medications. Researchers discovered that participants taking this drug for the year, lost weight within one month and have kept the weight off through the 56 weeks with the study. Contrave is really a combination in the drugs naltrexone and bupropion, which usually reflect a new trend of weight-loss drugs which can be made up of many active ingredient, which might make them more potent and safer. Combo-pilling could be the newest fad or also the newest into the future under scrutiny and thus it is just more publicly known lately, comb-pilling to lose weight has been around since the eighties. The biggest reason that employing a combination of pills is becoming popular is the fact that at the time of right now there aren't long term prescription weightloss pills that have been approved by the FDA besides orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications even though some of the combinations have been rejected or have yet to be authorized by the FDA. Seizures really are a side effect with Contrave and must not be taken in those with seizure disorders. The drug can also raise hypertension and heartrate, and mustn't be used in people with a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise hypertension and heartbeat and must not be used in patients with uncontrolled high hypertension, in addition to by a person with heart-related and cerebrovascular (circulation dysfunction impacting the mind) disease. Patients having a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes with a boxed warning to alert physicians and patients towards the increased likelihood of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stopping smoking. "There were no signs and symptoms of depression or suicidal thoughts in trial participants," said Fujioka.